ASXL1 (additional sex combs like 1) is a gene that is mutated in a number of hematological neoplasms.The most common genetic alteration is c.1934dupG p.Gly646fs.Previous publications have shown that ASXL1 mutations have a negative prognostic impact in patients with MDS and AML, however, controversy exists regarding the molecular testing of ASXL1 c.
Imran H Iftikhar,1 Franklin R McGuire,1 Ali I Musani21Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of South Carolina, Columbia, SC, USA; 2Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, CO, USABackground: Over the last several years, the
Growth, known as the relation between liveweight and age, is explained mathematically by functions that have parameters with biological meaning.These parameters are used to describe growth pattern over time and to estimate the expected weight of animals at specific ages.Animal growth generally follows a sigmoidal pattern and several nonlinear funct